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69 Glucocorticoids, immunosuppressants, and other drugs are commonly employed in clinical settings to manage GVHD
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Limitations include reliance on animal models (e.g., germ-free mice) that do not fully mimic human physiology, small human cohorts, and variable sequencing methods leading to non-reproducible taxa changes

Tirzepatide vs Retatrutide: The Big Differences at a Glance A big difference between these two meds is that tirzepatide is currently available (under the brand names Mounjaro and Zepbound) while retatrutide is still considered an investigational drug, undergoing clinical trials

These observations suggest that the mechanisms involved in humans may differ from the animal models
