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specifically the PKGI isoforms) and the phosphorylation of various protein substrates
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study used oral administration in rodents, which is part of what attracted research interest
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It increased surface GHRs in a biphasic manner, with a peak response at 10 nmol/L, and it modulated GH-induced Janus kinase-2 phosphorylation in parallel with the expression of surface GHRs [8]
