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Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM

[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Lemos, V

The likely-resulting endotoxemia from intestinal barrier dysfunction stimulates toll-like receptor 4 (TLR4) in Kupffer cells to produce NADPH-oxidase (NOX)-dependent ROS [213] and activate HSCs, leading to fibrosis [144, 219]

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Promotion of Angiogenesis: promotes the expression of VEGF to increase blood supply to damaged muscle tissue