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In AD patients blood cells, brain fibroblasts and fibroblasts cell lines as well as in cell line expressing mutant APP or treated with A, mitochondrial dysfunction has been reported

Although cysteine is incorporated into protein sparingly in a highly conserved manner due to its reactivity, protein synthesis accounts for the majority of cellular cysteine usage [9]

Exposure to organophosphate insecticides (OPs), the residues of which can be found on conventionally grown fruits and vegetables, induces oxidative stress by activating cytochrome P450 enzymes and by disturbing the cell redox system, which reduces cellular energy and makes cells unable to neutralize free radicals

Fallon, P

Cerebral ischemia-reperfusion therapy aims to mitigate or reverse brain injury but may paradoxically induce oxidative stress, inflammation and apoptosis, thereby exacerbating cerebral damage (189)