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The theory of free radicals of oxygen has been known for over 50 years, however, it is only in the last two decades that their role in the development of diseases were discovered and, thus, the beneficial effects of antioxidants have been widely studied (Liu, 2019)

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Lipoic acid prevents high-fat diet-induced hepatic steatosis in Goto Kakizaki rats by reducing oxidative stress through Nrf2 activation

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