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The unaffected CD38 binding of CD3813 in the presence of excess cold daratumumab suggests that CD3813 and daratumumab have distinct binding sites on CD38 [110]

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Candidates were excluded if they had a history of a neurological disorder that may better explain the results of the study such as epilepsy, brain trauma, neuropsychiatric disorder or mild cognitive impairment

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It can be caused by viral or bacterial infections, or by immune cells mistakenly attacking the brain

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