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Description
Positron emission tomography studies revealed that lack of sleep also causes inefficient glucose utilization especially in higher-order brain regions such as prefrontal cortex, thalamus, hippocampus and cortex that ultimately lead to impairments in cognitive functions (Wu et al., 1991

Q., Yu J

Covelli C, Sacchi D, Sarcognato S, Cazzagon N, Grillo F, Baciorri F, et al

High-throughput crystallography for lead discovery in drug design

They helped a little, or not at all, and now you're wondering if there's something you've been missing some option no one's actually explained to you yet
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