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That clue came about from research on a drug called bremelanotide, which was originally developed and tested as a sunless tanning agent
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F 2 -iPs are elevated in AD brain regions rich in the typical lesions such as frontal/temporal cortex and hippocampus but not in cerebellum, an area typically lacking senile plaques or NFT (293, 294)
It forms the backbone of many lipids that are termed glycerides
