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doi: 10.1111/1523-1747.ep12534670

Across all groups, fasting insulin levels decreased, suggesting improved insulin sensitivity

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found that irisin-mediated p53 reduction decreases ferroptosis and protects cardiomyocytes against high-glucose injury by increasing SIRT1, decreasing p53 K382 acetylation to promote p53 degradation, and consequently upregulating SLC7A11 and GPX4 [108]

Storage & Handling Store as directed Protect from direct light and excessive heat Keep out of reach of children Use within the recommended timeframe after opening For administration and dosing guidance, consult your healthcare provider