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Description
The nanoreactors can catalyze the oxidation of glutathione (GSH) to glutathione disulfide (GSSG) in hypoxic cancer cells
It interacts with DNA to form adductssuch as DNADNA and DNAproteins crosslinkswhich activate several signal transduction pathways that trigger cell death 74,76
That preclinical record is why clinicians and athletes took notice
Labeling and organization With multiple peptides, proper labeling becomes critical
PMID: 41255515 Proc Natl Acad Sci U S A Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway
