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Also, mice carrying a genetic mutation that lack one of the igf1r alleles ( igf1r +/ ) show a 10 % reduction in post-natal growth, insulin resistance and glucose intolerance [237]
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In breast cancer, mRNA delivery systems have shown superior pharmacokinetic profiles compared with synthetic antibodies that results in increased serum levels of therapeutic agents and improved tumor suppression with minimal adverse effects [349]
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References 1 AbdelgawadR.RathodY
