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However, confirming the up-regulated GST and GPx gene expression in pathogen-inoculated Tx7000 at 7 DPI, the functional assays provided evidence for enhanced GST-specific activity and GPx activity in both susceptible genotypes (Tx7000, BTx3042), leading to a net decline in GSH

Another study, involving the pharmacological blocking of endogenous melatonin production in rats, observed an increase in tau hyperphosphorylation

doi: 10.1172/JCI116109
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