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In an another study Sandeep et al

10.1038/s41467-019-12164-y 7 BoguslawskaJ.PoplawskiP.AlseekhS.KoblowskaM.Iwanicka-NowickaR.RybickaB.et al (2019)

Most patients are euthanized because of uncontrollable seizures or persistent neurologic defects

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Triggered by reactive oxygen species (ROS), the process begins with hydrogen abstraction from bis-allylic methylene groups, producing lipid radicals that react with molecular oxygen to form lipid peroxyl radicals
