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The C57Bl/6J strain, which is most often used for drug toxicity studies, has an average susceptibility to an APAP overdose [128]

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Bajic, V.P., et al., Glutathione Redox Homeostasis and Its Relation to Cardiovascular Disease

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The lower ascorbate accumulation of D dhar relative to the wild type was associated with a slight over-accumulation of threonate, an ascorbate degradation product

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For instance, while inhibiting CHAC1 may enhance cancer cell sensitivity to treatments, it could also undermine its protective role in conditions like neurodegenerative diseases where ferroptosis and oxidative stress are detrimental

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R.2000Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype.164(October 2000),297306,1059-7794 58

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