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Using human liver microsomes, it was also recently reported that sulforaphane metabolites (0-200 M) had little-to-no effect on the activities of CYP1A2, CYP2B6, CYP2D6, and CYP3A4 (23)
J Neuro-Oncol 9:3540
Among these, DNA methylation is the most extensively and well-researched form of epigenetic alteration
Its unique chemical makeup is what allows it to slip through cell membranes and interact directly with the NNMT enzyme
