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Future research should be focused on optimizing delivery systems to enhance bioavailability, developing combination therapies that leverage synergistic effects between natural compounds, and identifying specific asthma endotypes that may benefit most from these interventions

[27]Celi GEA, Grato PL, et al

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however, lack of interactions from the catechol group, as observed in docked poses and MD analysis, predicted to cause weak or no mh-Tyr inhibition by comparison to other selected flavonoids (EC and CH) due to rapid oxidation in the catalytic pocket of the mh-Tyr protein

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