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Deficiency in vitamin B12 is also associated with disproportionate fetal growth (low muscle mass and excess fat mass), increased insulin resistance, intrauterine growth restriction, and lifelong susceptibility to certain chronic diseases

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The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

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