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The mechanism by which HCV infection induces formation of membranous web in infected cells has been unknown yet, although NS4B is involved in formation of membranous web (Egger et al., 2002
Nawrocki, K
doi: 10.1021/ac300540r
Most studies involve small sample sizes, short durations, or lack control groups, which hampers the ability to draw definitive conclusions
Using streptavidin-alkaline phosphatase conjugate and a biotinylated secondary antibody, immunohistochemistry was carried out on the sections after the primary antibodies had been incubated for an overnight period
