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It is mainly known for its role as one of the circadian rhythm regulators, primarily synthesized in the pineal gland by pinealocytes under dark conditions (69)

Protective effect of alpha-lipoic acid against apical periodontitis-induced cardiac injury in rats

Exposure to these infectious pathogens and inflammatory stimuli can profoundly affect the brain and behavior ( Toxoplasma gondii infection, which, in animal models, alters behavior and increases the release of neurotransmitters such as dopamine, and the amount of dopamine release is correlated with the number of infected cells ( + T cells, which are crucial for sustaining lasting immunity, have been found to be downregulated in schizophrenia patients ( Toxoplasma gondii infection has been shown to affect the gut microbiome in mice ( Table 1 Clinical evidence for the association between infectious pathogens and schizophrenia

Thioredoxin reductases (Trx1, Trx2, and Trx3) reduce disulfides to oxidize thiol-dependent peroxidases, thereby exhibiting antioxidant activity as well (Lu and Holmgren, 2014)

These values are presented in Figure 1 [12,13,14,15,16,17,18,19,20,21,31]