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In this review, we first scrutinize the research process of NF-B signaling, and summarize the composition, activation, and regulatory mechanism of NF-B signaling

It examines how conventional cancer treatments, chemotherapy, radiotherapy, and immune checkpoint inhibitors, exacerbate dysbiosis and NF-B-driven inflammation, further complicating treatment outcomes

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BPC-157, derived from a protective protein in gastric juice, and TB-500, a synthetic fragment of Thymosin Beta-4, have both been investigated for their potential roles in healing, tissue repair, and cellular regeneration
