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Consistent with a shift away from glucose utilization, BHB levels were elevated in brain extracts from BAD knockout animals, a result that is reminiscent of the characteristics of the ketogenic diet

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It also impacts cellular signalling in brain tissue, with potential applications in targeting neurodegenerative diseases and alleviating brain fog

Stimulation of TLR4 generally induces the production of pro-inflammatory cytokines, modulates expression of associated receptors (e.g., TLR2), and facilitates immune cell recruitment, culminating in coordinated effector immune responses in systemic organs such as the spleen

Manzoor N, Liaqat A, Ahmed T, Noman M, Adrees M, Shahid MS, et al