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Studies using several mouse models of psychiatric disorders, such as the Ca 2+ /calmodulin-dependent protein kinase II (-CaMKII) heterozygous knockout, showed that the dentate gyrus granule cells were arrested at a stage with similar molecular and physiological properties to those of the immature neurons (Yamasaki et al., 2008
However, it is important to note that hydroxocobalamin is not effective in treating pernicious anemia, which is caused by an autoimmune disorder
& Rice, C
Medicine (Baltimore), 97 (27): e11390
