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1) and other related metabolites, we further conducted metabolomics analyses by using Abcg2 knockout (KO) mice and Eisai Hyper-bilirubinemia Rats (EHBR is an Abcc2- deficient animal model), because both two ABC transporters play a pivotal role in ATP-dependent biliary excretion of conjugated xenobiotics as components of Phase III machinery

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doi: 10.1016/J.tips.2016.01.002

Nirmala JG, Lopus M