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Broad, E

doi: 10.3402/mehd.v26.28177
It can destroy lipids, DNA, and protein, and trigger apoptosis by inducing cytochrome c release from the mitochondria [153]

Also, creatine is responsible for water retention on the skin which may lead to inflammation

Investigations such as these could reveal new therapeutic targets for improving cardiac metabolic pathways and devising new interventions for cardiovascular management