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They are rare but serve as a warning against long-term abuse
Treatment 2.3.4.1
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Circulation 108:19121916 Shiomi T, Tsutsui H, Matsusaka H, Murakami K, Hayashidani S, Ikeuchi M, Wen J, Kubota T, Utsumi H, Takeshita A (2004) Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice
NLRP3, NOD-Like Receptor Family, CARD Domain-Containing Protein 4 (NLRC4), and AIM2 inflammasomes activate caspase-1, which cleaves pro-IL-1 and pro-IL-18 into their mature forms (139, 140)
