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This distinguishes it from GLP-1 medications, which in some patients have been associated with significant lean mass reduction alongside fat loss

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These conventional treatment options include: Nonsteroidal anti-inflammatory drugs Muscle relaxants Physical therapy Surgery Nonsteroidal Anti-Inflammatory Drugs Over-the-counter anti-inflammatory drugs such as acetaminophen have been considered the medications of choice in the management of the many conditions that manifest as low back pain, including piriformis syndrome