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Barthel, A., Schmoll, D

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Due to the poor bioavailability and interconversion of these precursors, more potential NAD + precursors and intervention strategies are sought that have higher potency and stability

Treatment with 5-amino-1mq upregulates proliferationrelated genes (Ki67, PCNA), promotes cell cycle progression, and improves cell fusion efficiency to form more multinucleated myotubes, achieving functional levels similar to those of young mice.Additionally, 5-amino-1mq inhibits muscle stem cell apoptosis, reduces oxidative stress damage, and maintains stemness