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Unlike Viagra (which only affects blood flow), PT-141 works in the brain to increase actual arousal and desire

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Who Should Be Cautious With FOXO4-DRI Because there is no human safety data, the cautions below are drawn from the compound's mechanism and from general research practice, not from clinical findings

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Patients can present with the following signs & symptoms: CNS (areflexia, asthenia, ataxia, blurred vision, disorientation, dizziness, drowsiness, hyporeflexia, slurred speedh, somnolence, staggering, tiredness, coma) Cardiovascular (initial hypertension, followed by long-lasting hypotension , bradycardia , premature ventricular beats) the peripheral actions of xylazine cause an initial increase in blood pressure, followed by central effects that result in a long-lasting hypotensive effect, accompanied by bradycardia and reduced cardiac output (Hoffman et al, 2001)

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Modulations of gene expression related to inflammatory signaling, angiogenic regulators, cell cycle control, and structural matrix proteins have been documented in preclinical and in vitro systems

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Nature 593 , 580585 (2021)

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