glutathione peroxidase inhibitor GPX4 17 (Glutathione 4-IN-17, Peroxidase 4 Inhibitor 17, GPX4-IN-17) of the mechanism of ferroptosis

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This is where Phase II detoxification, specifically a process known as glutathione conjugation, becomes critical

doi: 10.1055/s-0035-1548790 143 JamilianMRazaviMFakhrie KashanZGhandiYBagherianTAsemiZ

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www.sciencedirect.com Nrf2 (nuclear factor erythroid 2-related factor 2) is a cellular protein that regulates the expression of antioxidant and stress response proteins