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Rastgoo, S., Fateh, S

Urine analysis demonstrated a strikingly high excretion of uracil 84.8 mmol/mol creatinine (0-15.1 mmol/mol creatinine), orotic acid 11.6 nmmol/mol creatinine (0-1.2 mmol/mol creatinine) and uridine 9.1 mmol/mol creatinine (0-3.7 mmol/mol creatinine)

A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)