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Reid, K

However, when SOD activity increases, the enhanced levels of H 2 O 2 trigger the upregulation of CAT [11] and/or GPx [12], with a final antioxidant balance as a compensatory and defense response strategy

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At maintenance or surplus, you may see improved insulin sensitivity and mitochondrial function, but fat loss will be minimal without negative energy balance

Specifically, dysfunction of the BER pathway can lead to ineffective repair of oxidative DNA damage, and unrepaired SSBs may progress into more cytotoxic DSBs (127,128)