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Its anti-neoplastic effects are related to the pro-angiogenic factors and growth inhibition, induction of endothelial cells apoptosis through a p53-dependent pathway involving Bcl-2/Bax, cytochrome C release, Apaf-1, and activation of caspase-3 and PARP (3,14)

\Potential Diabetes Remission: Through insulin sensitization, glucagon suppression, and beta-cell support

Facilitate the blinding of the identity of treatment to investigators, participants, evaluators

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