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Quantification of GFP-tagged stress proteins and data handling were conducted as previously described ( Statistical Analysis Statistical analysis was conducted using Prism (version 5.0)
Tregs can also directly inhibit natural killer (NK) cell effector functions by the down-regulation of NKG2D receptors on the surface of NK cells caused by membrane-bound TGF- on Tregs (231)
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As for the possible mechanism, GR-induced CLU upregulation was shown to inhibit DNA damage-induced apoptosis through mechanisms involving e.g., stabilization of Ku70 (70 kDa subunit of Ku antigen) and Bcl-2-associated X protein (Bax) interaction, which prevents its translocation to the outer mitochondrial membrane and subsequent release of cytochrome c (cyto c ) [178]
Curcumin Curcumin, a polyphenolic compound derived from turmeric, is widely studied for its antioxidant and anti-inflammatory properties
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