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Current drug metabolism

The NQO1 bioactivatable drug, -lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism

[DOI] [PMC free article] [PubMed] [Google Scholar] 65.Teape D, Peterson A, Ahsan N, Ellis K, Correia N, Luo R, et al

The dose matters