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The FDA considers it a non-toxic substance under the Generally Recognized as Safe (GRAS) classification for specific applications

This effect lasted 20 minutes in 1K1C rats or 12 hours, at least, in 2K1C animals

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MTT assay (viability assay) SH-SY5Y cells were seeded in 48-well plates (Corning) (2 10 5 cells/200 l/well) in DMEM containing 10% FBS, 10 3 M l-glutamine in a 5% CO 2 incubator at 37 C

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