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PMID: 87 ZhouMZhengMLiangSLiMMaJZhangSet al

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Moreover, release of nitric oxide (NO), a soluble gas produced by endothelial cells, and also endothelial-dependent hyperpolarization can negatively modulate myogenic tone by acting directly on SMCs (75)

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27 There was a 20% absolute increase in patient-perceived improvement in the short term and a 30% absolute increase in the long term

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This mechanism is followed by the activation of the influx of calcium and secretion of brain-derived neurotrophic factor (BDNF)

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PLoS One 11 (9), e0163806

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