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Abstract Nuclear factor erythroid 2-related factor 2 (NRF2) is a stress responsive transcription factor that is mutationally activated in a subset (~25%) of clinically-aggressive non-small cell lung cancers (NSCLC)

A study using a combination of NAC with a high dose of naltrexone (150 mg) compared the combination group against two groups of patients receiving a high dose of naltrexone and a low dose of naltrexone (50 mg) alone, evaluating the percentage of heavy drinking days, measured using the timeline follow back (TLFB) method, over 12 weeks

2.4 Modulators of the expression of EAATs The expression of EAATs is altered in certain disease states, leading to changes in neuronal excitation

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