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[] Intravenous glutamine can reduce lipid peroxidase production and increase tight junction gene expression in kidney cell walls to reduce macrophage-neutrophil infiltration and inflammation pathways

Tiwari A, Modi SJ, Girme A, Hingorani L

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For example, during the early stages of AD, deoxycholic acid accumulates in the brain and can directly impair cognition by binding with the bile acid receptor Takeda G protein-coupled receptor 5 (TGR5) on excitatory neurons, leading to STAT3 phosphorylation, Aph1 transcription, and increased A production [220]