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Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy)

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The amplification was performed by using TaqMan gene expression assays (Hs00167309, Hs00156308, Hs01110250, Hs00195591, Hs01566408, Hs04989912, Hs00958111, Hs04189111, Hs00426835, and Hs99999905) according to the manufacturers instructions