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Hexarelin is a research compound and an unapproved substance in the United States, discussed in some peptide-therapy and anti-aging clinic literature for off-label muscle growth and recovery use, not an over-the-counter bodybuilding supplement

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investigated the in vivo effects of intradiscal administration of osteogenic protein-1 (OP-1) and transforming growth factor-beta (TGF-) into the IVDs of rabbits