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Although human epidemiological studies are being conducted to address the effect of repetitive blasts (e.g., with Marines) and a longitudinal study is being carried out with combat veterans and retired athletes (see Stern et al., Appendix C), there is also a need for animal models that replicate repetitive TBI in humans
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Vitamin C and niacin further enhance metabolic and cellular protection

The anti-inflammatory effects were equally notable, with lower interleukin-1 and tumour necrosis factor-alpha levels, highlighting curcumins ability to disrupt the cycle of inflammation that fuels both insulin resistance and hepatic damage