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Insufficient Water Volume 0.5mL added to a 5mg vial yields 10,000mcg/mL

For example, a healthy person taking a 500 mcg oral B12 supplement will only absorb about 10 mcg
Each cellular compartment has different ratios

References 1 Endocrine Reviews (Oxford Academic)Comprehensive review of kisspeptin and neurokinin B: role in reproduction and emerging therapeutic potential
