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Through the precise regulation of carnitine levels, new treatments can be developed for these complex diseases, and more effective interventions can be provided for patients (Fig

doi: 10.3390/nu11040811 [DOI] [PMC free article] [PubMed] [Google Scholar] 111.Di Lorenzo C, Coppola G, Sirianni G, Di Lorenzo G, Bracaglia M, Di Lenola D, et al

Jun 2021;139:109722

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Follow-up studies for 4 and 7 years after the intervention with 500 mg/day for 9 months showed that sustained cognitive benefit was associated with potential improvements in associated white matter microstructure in the choline group (170, 171), which suggests that choline supplementation has the potential to alter brain architecture