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However, because the need for chronic cobalamin supplementation may concern a significant number of people [8], and alternative therapy does not occur, this problem seems to be so important that several different strategies for desensitization of patients requiring cobalamin treatment, who have been diagnosed with hypersensitivity to vitamin B12 [9,10,11,12,13,14,15,16], which are presented above
Kricha A, Bouchmaa N, Ben Mkaddem S, Abbaoui A, Ben Mrid R, El Fatimy R (2024) Glioblastoma-associated macrophages: a key target in overcoming glioblastoma therapeutic resistance
doi: 10.1093/braincomms/fcad353 154 BudimirovicDBDominickKCGabisLVAdamsMAderaMHuangLet al
Such methods can also be personalized to understand the specific behavior of particular GMOs by incorporating their unique biochemistries to discover other relevant and more specific biomarkers, beyond the two identified from this effort

HCC is a complex and heterogeneous tumor characterized by multiple genetic mutations in genes controlling cell proliferation, cell death, homeostasis and oxidative stress [305]
