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Two distinct domains are recognized in each GST monomer: a N-terminal thioredoxin-like domain and a C-terminal alpha-helical domain

Zoidis E, Seremelis I, Kontopoulos N, Danezis GP (2018) Selenium-dependent antioxidant enzymes: actions and properties of selenoproteins

One of the primary areas for concern involves pre-existing metabolic dysregulation

Research has shown that both knockout and deletion of the LRP8 gene can trigger ferroptosis [139, 140]
