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doi: 10.22099/IJVR.2021.39045.5677
Bibcode:2008Aquac.284..190H
The increased oxidative environment resulting from NOX activity and mtROS production leads to GSH depletion
PGC-1 is a key controller of mitochondrial biogenesis and the reactive oxygen species (ROS) stress response and is controlled by SIRT1/3, TFAM, and AMPK
Common stressors linked to mitohormesis include environmental toxins, dietary factors, cognitive stimulation, physical exercise, extreme temperatures, and hypoxia [157, 166,167,168]
