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We also found that induction of autophagy by IAP was dependent on signaling through TLR4, a pattern recognition receptor, as IAP failed to activate autophagy in the presence of TLR4 inhibitor C34
Moreover, it has been found that mitochondrial functions and integrity can be affected by many of the risk factors of ASD, including toxins, immune activation, medicines, and metabolic disturbances [17]
doi: 10.1016/j.conb.2004.05.007
It's a pro-oxidative gene
, antibody, DNA/RNA strands, aptamers, etc
