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If necessary, we may also recommend blood testing or liaising with your GP

The most robust theory is that metformin disrupts the B12-intrinsic factor (IF) complex uptake at the ileal cell surface receptor (Cubilin receptor) which is known to be calcium dependent

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Those with Chronic Fatigue : If youre constantly feeling tired, even after a full nights sleep, low B12 levels could be to blame

Regulating metabolic pathways
