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The severe insulin-deficient diabetes (SIDD) subtype is characterised by high HbA 1c , low HOMA-B and low HOMA-IR , resembling adult-onset type 1 diabetes but in the absence of autoantibodies

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Both have virtually identical values (3.2 eV) but significantly different in vivo toxic potencies (LD 50 = 5.2 mmol/kg vs 18 mmol/kg, respectively)

Other factors remaining constant, the concentrations of the two forms modulate the effective redox potential of the couple according to the relationship [GSH] 2 /[GSSG] (Meyer, 2008)

Increased meningeal t and plasma cell infiltration is associated with early subpial cortical demyelination in common marmosets with experimental autoimmune encephalomyelitis