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CREDENCE (Perkovic et al, NEJM 2019, NephJC summary) was the first study to focus on patients at high risk of kidney outcomes and promote those outcomes to the primary end-point

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When a surgeon evaluates a patient and decides during that visit to perform a major procedure the same day or the next, the E/M visit that led to the decision uses modifier 57

In this study, a rapid rate of eGFR change during the first year of the trial was defined as a 10%/year decline [4, 19]

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